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Sunday, June 17, 2018

Hypoxic & Hyperoxic Guard


Predicted PaO2 Table setup as a Hypoxic & Hyperoxic Guard. 

Maximizing oxygenation to prevent hypoxia and hyperoxia can be accomplished by titrating FiO2 to target a optimal paO2 goal. Practitioners often consider a liberal oxygenation strategy of a target SPO2 > 95% & consider hyperoxemia acceptable. Conversely, "hyperoxia and hyperoxemia may promote lung injury during mechanical ventilation and lead to poor outcomes" [1].

The above table "Predicted PaO2" from my new reference [1] is color-coded and setup as a "Hypoxic & Hyperoxic Guard", the tables are based on a more conservative oxygen strategy of a PaO2 target of 60-100. Additionally, the tables
where created using a newer formula which allow for more accuracy in the presence of shunts.


Inputs- Old FiO2 (starting FiO2), Old PaO2Outputs- predicted PaO2 for new FiO2 settings 25-100%

1. Richey KS. Lung Protective Tabulations, 2018